Endocrine Abstracts

Bone mass density and beta cross laps have been recognized as valid tests for the diagnostic and treatment control, as well as fracture prediction for osteoporotic patients. Statin treatment has been reported to be associated with a reduced risk fracture in these patients also. However, no studies, as of our knowledge, have tried to see if adding the lipid profile to the analysis of body mass density would improve the statistical power of prediction for any of the afore mentio...

Aim: To re-analyze the concept of echographic thyroid patterns (ETP) and clinical diagnostic in thyroidology, proposed 10 years ago.Material/method: i) Between 1996 and 2012, >25 000 thyroid ultrasound, linear probes, 7.5 MHz. ii) Description – eight ETP: pattern 0 – lack of thyroid, 1 – hypoechogenous pseudonodular; 2 – hypoecogen homogenous; 3 – micronodular hypoechogenous; 4 – macro (> 10 mm; ±micro) nodular;...

Objectives: To investigate how the immune associations (IA) may have significance for diagnosis or therapy in thyroiditis.Material and method: Patients: A. ‘Classical’ Hashimoto thyroiditis (hyper-ATPO-emia, HT) =1092, B. thyroiditis with isolated hyper-ATG-emia, with normal ATPO (T-ATG) =61, C. thyroiditis ‘sero-negative’ (normal ATPO and ATG, pathology diagnosis) =5, D. idiopathic myxedema (hypothyroidism, no A, B,C) =70; E. control...

Aim and objectives: To investigate the rapport between the level of thyroid function, through blood level of TSH, both at onset, and in evolution and the level of antithyroperoxydase antibodies (ATPO) and antithyroglobuline antibodies (ATG) in Hashimoto thyroiditis and related diseases.Material and method: Diagnosis: a. ATPO >34 μ/ml = Hashimoto thyroiditis (HT); b. ATPO=normal with high ATG = thyroiditis with only hyper-ATG (T-ATG); c. hypothyr...

Aim: Analyzing the evolution of thyroid function in thyroiditis and related disease during 1–15 years.Materials and methods: A) Diagnostic: Hashimoto thyroiditis (HT): i) antithyroperoxydase antibodies (ATPO) cut-off 34. ii) If ATPO=normal (N), was considered thyroiditis with only antithyroglobuline antibodies (T-ATG); iii) idiopathic mixedema (IM): hypothyroidism, no ATPO, no ATG, no TRAB.B) Patients: i) HT: 1092; T-ATG: 61; ...

Aim, Objectives: Conceptualizing new data related to type and level of autoantibodies in thyroiditis Hashimoto, Graves-Basedow disease and releated conditions.Material: ###1. Adoption the integrative concepts of immune network (Nobel Prize, 1984) for immune thyroid diseases. 2. Searching on “www.ncbi.nlm.nih.gov/pubmed” for papers with keywords: thyroid autoantibody, thyroiditis (~2500 papers). 4. New (auto)-antibodies (and antigens/epitopes) f...

Introduction: Exogenous Cushing’s syndrome is a challenging diagnosis in non-compliant patients or in cases with difficult anamnesis, while the access to self medication is relatively open.Aim: We present a young female case presenting with tertiary adrenal insufficiency.Case report: S.C., 40 years old has progressively weight gain of 30 kilos since the last year. The Body Mass Index is 40 kg/m2, with androgen redis...

Introduction: The heel Quantitative Ultrasound (QUS) evaluates the bone health, with good results if the clinical risk factors are also evaluated for each patient. Among these, the body mass index (BMI) may be protective or risk factor for a fragility fracture, depending on the values.Aim: We present a study in postmenpausal women evaluated by QUS and BMI.Patients & method: This is a study in 330 patients (women in menopause wh...

Introduction: Infertility investigations include uterine–ovarian ultrasound. The incidental finding of a tumor in a young female might associate a potential severe prognosis in otherwise completely asymptomatic patient.Aim: We present a case of a young female with an accidentally discovered ovarian tumor.Case report: S.M. 35-year female patient is admitted for infertility. Her family and personal medical history is irrelevant....

Introduction: Pituitary incidentaloma is a relatively frequent imagistic finding. Since no therapy is necessary, the follow up protocol is the most important in patients’ approach.Aim: We present a study in patients diagnosed with pituitary incidentaloma, admitted in I.Parhon, Bucharest, between 1999 and 2011.Patients and method: This is a retrospective study in 140 patients, diagnosed with pituitary incidentaloma based on CT ...